A Global Study Uncovers Genetic Risk Factors for Alzheimer’s Disease
A comprehensive international study, involving the University of Cologne, has investigated genetic risk factors for Alzheimer’s disease in various population groups. Researchers have discovered that, in addition to the well-known APOE gene, approximately 75 other genetic variants worldwide are linked to the condition. The findings were published in the scientific journal Nature Genetics.
The study reveals that the genetic risk factors are similar in most population groups, while the APOE gene has different effects. This could explain the varying Alzheimer’s risk in different ethnic and regional groups. The researchers emphasize the importance of such studies for the development of targeted treatment methods.
Alfredo Ramirez from the University of Cologne noted that the study underscores the need for integrated research. Previously, primarily people of European descent had been studied. The new findings could contribute to improving health equity and advancing the treatment of Alzheimer’s worldwide.